Analytical method for the determination of 4,4'-methylene-bis(N,N-dimethylaniline)

Translation of DGUV Information 213-557 (former BGI 505-57 or ZH1/120.57)

CAS Number: 101-61-1

Synonym: Bis(4-dimethylaminophenyl)methane


Method 01 – HPLC

Sampling with a pump and absorption on an impregnated filter, high performance liquid chromatography (HPLC) after desorption.

This method permits the determination of 4,4'-methylene-bis(N,N-dimethylaniline) concentrations in working areas averaged over the sampling time after personal or stationary sampling.

Principle

With a pump a measured air volume is drawn through a glass fibre filter impregnated with sulfuric acid. The adsorbed 4,4'-methylene-bis(N,N-dimethylaniline) is eluted with water and analysed by high performance liquid chromatography. 

Limit of quantification (LOQ)

Absolute:  0.09 µg 4,4'-methylene-bis(N,N-dimethylaniline).

Relative: 0.015 mg/m3 for 500 L air sample, 4 mL desorption solution and 50 µL injection volume.

Issue

June 1995 

The complete measuring method is available in the Wiley Online Library: Method for the determination of 4,4'-methylene-bis(N,N-dimethylaniline) (Analyses of Hazardous Substances in Air, Volume 4, 1999).

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