Analytical method for the determination of 4,4'-methylene-bis(N,N-dimethylaniline)
Translation of DGUV Information 213-557 (former BGI 505-57 or ZH1/120.57)
CAS Number: 101-61-1
Synonym: Bis(4-dimethylaminophenyl)methane
Method 01 – HPLC
Sampling with a pump and absorption on an impregnated filter, high performance liquid chromatography (HPLC) after desorption.
This method permits the determination of 4,4'-methylene-bis(N,N-dimethylaniline) concentrations in working areas averaged over the sampling time after personal or stationary sampling.
Principle
With a pump a measured air volume is drawn through a glass fibre filter impregnated with sulfuric acid. The adsorbed 4,4'-methylene-bis(N,N-dimethylaniline) is eluted with water and analysed by high performance liquid chromatography.
Limit of quantification (LOQ)
Absolute: 0.09 µg 4,4'-methylene-bis(N,N-dimethylaniline).
Relative: 0.015 mg/m3 for 500 L air sample, 4 mL desorption solution and 50 µL injection volume.
Issue
June 1995
The complete measuring method is available in the Wiley Online Library: Method for the determination of 4,4'-methylene-bis(N,N-dimethylaniline) (Analyses of Hazardous Substances in Air, Volume 4, 1999).
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