Analytical method for the determination of 1,5-diaminonaphthalene
Translation of DGUV Information 213-563 (former BGI 505-63 or ZH1/120.63)
CAS Number: 2243-62-1
Synonym: 1,5-Naphthylenediamine
Method 01 – HPLC
Sampling with a pump and adsorption on an impregnated filter, high performance liquid chromatography (HPLC) after desorption.
This method permits the determination of 1,5-diaminonaphthalene concentrations in working areas averaged over the sampling time after personal or stationary sampling.
Principle
With a pump a measured air volume is drawn through a glass fibre filter impregnated with hydrochloric acid as stipulated in the definition of inhalable dust fraction. The adsorbed 1,5-diaminonaphthalene is desorbed with a mixture of acetonitrile and aqueous ammonia and analysed by means of high performance liquid chromatography (HPLC).
Limit of quantification (LOQ)
Absolute: 20 ng 1,5-diaminonaphthalene.
Relative: 0.016 mg/m3 1,5-diaminonaphthalene for 500 L air sample, 5 mL desorbate (dilution in the ratio 1 :1 v/v) and 25 µL injection volume.
Issue
December 1998
The complete measuring method is available in the Wiley Online Library: Method for the determination of 1,5-diaminonaphthalene (Analyses of Hazardous Substances in Air, Volume 5, 2002).
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