Analytical method for the determination of carboxylic acid amides
Translation of DGUV Information 213-574 (former BGI 505-74)
| Chemical name | CAS Number |
|---|---|
| N,N-Dimethylacetamide | 127-19-5 |
| N,N-Dimethylformamide | 68-12-2 |
| N-Methylformamide | 123-39-7 |
| Formamide | 75-12-7 |
Method 01 – GC
Sampling is carried out with a pump with the particulate fraction being collected on a glass fiber filter and the gaseous fraction adsorbed on charcoal. Analysis is performed by gas chromatography after desorption.
This method can be used with personal or stationary sampling to determine the mean concentration of the carboxylic acid amides N,N-dimethylacetamide, N,N-dimethylformamide, N-methylformamide and formamide at the workplace over the sampling time.
Principle
A pump draws a defined volume of air through a GGP system equipped with a glass fiber filter and a tube filled with charcoal. Then the collected carboxylic acid amides are desorbed with a mixture of dichloromethane and methanol and analysed by gas chromatography.
Limit of quantification (LOQ)
Absolute: 1.1 to 15 ng for each carboxylic acid amide.
Relative: 0.1 to 1.3 mg/m3 for each carboxylic acid amide based on an air sample of 120 L, a sample solution of 10 mL and an injection volume of 1 µL.
Issue
April 2008
The complete measuring method is available in the Wiley Online Library: Method for the determination of carboxylic acid amides (Air Monitoring Methods, Volume 13, 2012).
You can reach the German-language version of the article with a single click on the flag-symbol.
